Researchers have recently reported that Poliovirus can also kill cancer cells or at least stop the growth of the tumor. The research happened in Durham’s Duke University. The team that proved the findings was led by Dr. Matthias Gromeier, Neurosurgery professor and Prof. Smita Nair an immunologist from the department of surgery. The research shows that a modified polio virus helps the body to develop its own resources to kick off cancer. It is pretty revolutionary as the new form of the poliovirus has been under research in clinics since 2011. It has not shown any significant side effects for the patient.
The clinical trials recently got concluded with these fantastic findings. The new variant is known by the name recombinant oncolytic poliovirus. Researchers are still on their way to fully understand the functioning of revised poliovirus form. It cannot be circulated independently until the working methodology is proved. Once it gets fully confirmed it will be a huge gift to humanity as cancer is one of the top reasons for deaths today. The rationale was explained by the team leads as to improve the survival condition of the cancer patients. The new immune response of the patient due to this drug will help cure cancer to a great extent. In some cases, it might allow total recovery.
The new polio virus works by inhibiting re-growth of the tumor and attacking the current one. Scientists observed the effect of poliovirus on two kinds of cancer cells a triple negative breast cancer and melanoma. It showed that the polio virus works by attaching itself to the cancer cells. Since the cancer cells have CD155 protein, it tends to be receptive to the polio virus. In this way, the poliovirus starts attacking the cancer cell triggering the release of antigens from the tumor cells. The process is a lot more detail to understand. However, the concept does give us hopes for the future to treat cancer patients.
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